Parallel Artificial Membrane Permeability Assay (PAMPA)Permeability and Transporters
• High-through put assay
• Evaluation of passive permeation
As a high-throughput screening permeability assay, we offer the Parallel Artificial Membrane Permeability Assay (PAMPA). This assay is used as an in vitro model for passive, transcellular permeation. It is a fast and easy method which determines the permeability of test compounds from a donor compartment, through a lipid-infused artificial membrane into an acceptor compartment. PAMPA studies are performed using the PAMPA explorer kit (pION Inc) and the double sink protocol.