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Admescope Blog

Metabolites in safety testing (MIST)

5 February 2019

After administration into a body, the drug is usually metabolised into metabolites, which may also be associated with toxic effects. This is why the MIST strategy has evolved to ensure that human metabolites have been adequately covered in the preclinical safety studies. Admescope site manager Sweden Dr Johanna Haglund will describe how to tackle this question.
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Tags: , in vivo DMPK